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Showing posts with label genomics. Show all posts
Showing posts with label genomics. Show all posts

Sunday, June 02, 2013

MooPig Cloning Department :: "Woolly Mammoth?"

The Rest is History
Cloned article by Pat Darnell  |  June 2, 2013  |  Bryan TX


[Picture LINK] 'We were really surprised to find mammoth blood and muscle tissue,' said Semyon Grigoriev, head of the Museum of Mammoths of the Institute of Applied Ecology of the North at the North Eastern Federal University. Picture: Semyon Grigoriev

We are noncommittal when it comes to cloning articles, which is what out MooPig Cloning Department usually does. But we didn't know which department to refer this story to, since we don't have any scientists aboard MooPig central. So we sent it to the cloning department.

Also we are sorry this LINK to The SUN is intermittent valid; we try to stay current... but alas we were too slow. Sometimes the Link works, sometimes it doesn't.

Now, we are just showing off. How does this fit into the current flow of things, having a blood sample from an extinct animal? You ask? No? Oh, but it does figure in.

While the world of humans tumbles into obscurity, making humans the next big Extinction Level Event on Earth, we should go out with at least a few Wooly Mammoths around. Their remains will totally confuse the next gen of humanoid explorers, as they try to piece together ancient times.

Woolly mammoth found with blood in veins boosts chance of cloning | The Sun |News: "Hwang Woo Suk, a stem cell scientist who created the world’s first cloned dog in 2005, said that once the tissues had been treated to a nuclear transfer process, eggs would be implanted into the womb of a live elephant for a 22-month pregnancy. Semyon Grigoriev, chairman of the university's Museum of Mammoths and head of the expedition, said: "The fragments of muscle tissues, which we've found out of the body, have a natural red colour of fresh meat."

'via Blog this'
" ... A perfectly preserved woolly mammoth carcass with liquid blood has been found on a remote Arctic island, fueling hopes of cloning the Ice Age animal, Russian scientists said Thursday.

The carcass was in such good shape because its lower part was stuck in pure ice, said Semyon Grigoryev, the head of the Mammoth Museum, who led the expedition into the Lyakhovsky Islands off the Siberian coast.

"The blood is very dark, it was found in ice cavities below the belly and when we broke these cavities with a poll pick, the blood came running out," he said in a statement released by the North-Eastern Federal University in Yakutsk, which sent the team.

Wooly mammoths are thought to have died out around 10,000 years ago, although scientists think small groups of them lived longer in Alaska and on islands off Siberia. (abc13. Wednesday, May 29, 2013. LINK) ... "
CONCLUSION
We don't know what we are talking about, do you?


______________________Reference
http://www.thesun.co.uk/sol/homepage/news/4948104/Woolly-mammoth-found-with-blood-in-veins-boosts-chance-of-cloning.html
http://abclocal.go.com/ktrk/story?section=news/national_world&id=9121884
http://siberiantimes.com/science/casestudy/news/exclusive-the-first-pictures-of-blood-from-a-10000-year-old-siberian-woolly-mammoth/

Monday, December 31, 2012

MooPig Moment of Science Department :: "2012 Highlights"

Welcome to the Age of Trans-humanism
Retrieved by Pat Darnell  |  Dec 31, 2012  |   Bryan TX

Business Insider has made a beautiful slide show for this year's best moments in science. If we could just put it all together, shake out all the old gray matter, and apply these discoveries, we might survive the next hundred years.

Humanity is a blip on the radar screen, in the overall scope of earth's history. Yet, already we are stumbling into trans-humanism, augmented human action using technology, implants and thought capturing sensors.

And was that the God particle after all? The good thing about science is that most of the time you can be assured that people are telling the truth.

Science's 2012 Breakthroughs Of The Year - Business Insider:


The discovery of the Higgs boson confirms mainstream physics theories.
On July 4, scientists at the European Center for Nuclear Research, or CERN, in Geneva announced with near certainty that they had found a Higgs boson. The Higgs boson is a big deal because it provides proof of an invisible field that gives mass to matter. The theory "explains how particles interact via electromagnetic forces, weak nuclear forces and strong nuclear forces in order to make up matter in the universe," writes Science.

NASA's Mars Curiosity rover lands on Mars.
A special "sky crane" landing system placed NASA's Curiosity rover on Mars on Aug. 5. The complicated landing maneuver was famously dubbed the "seven minutes of terror" by NASA engineers because that's how long it took Curiosity to get from the top of the Martian atmosphere down to the surface of the Red Planet. The mission control team had no contact with the one-ton robot during those critical minutes.
Curiosity survived the landing with 100 percent working parts, and is going strong five months into her two-year mission on Mars, sending back new photos and crucial data for future space travel each day.

'via Blog this'

Scientists created eggs from mice stem cells for the first time.
Japanese researchers showed that embryonic stem cells from mice could be made into viable egg cells, that could be fertilized and result in healthy babies. The healthy mouse pups shown here were bred from the eggs they created. The experiment only involved mice, but may one day be used to treat infertility in humans.

Scientists discovered the structure of a protein involved in the transmission of African sleeping sickness.
Membrane proteins span the outer shell of each and every cell in our bodies, sending signals and shuttling stuff between the inside of the cell and the outside. These proteins play a role in almost everything the cells do, and their involvement is critical in the transmission of diseases and disease-fighting drugs, so understanding their structure is important for developing new drugs to target the disease.
Researchers used an X-ray laser a billion times brighter than traditional X-ray sources to provide a detailed structure of one of these membrane proteins, which plays an important role in the transmission of the parasite that causes African sleeping sickness, a disease that kills around 30,000 people each year. This finding
The enzyme is shown spiking out of the insect's cell membrane below.

Sub-atomic particles known as neutrinos are caught changing from one type to another.
Some nuclear reactions, including those that take place inside the sun, create neutrinos. Neutrinos and their corresponding antineutrinos come in three basic “flavors": electron, muon and tau.
Measurements from the Daya Bay Neutrino Experiment in China revealed how electron antineutrinos transform into different flavors — either muon or tau — as they travel at the near-speed of light.
The results could help explain why the universe contains so much more matter than antimatter.

Researchers sequenced the genome of the Denisovians, a group of ancient humans that lived 41,000 years ago in Siberia.
Along with the sequencing of the Neanderthal genome, researchers also sequenced the genome of the group of ancient humans named the Denisovians, who lived 41,000 years ago in Siberia.
They isolated DNA from a bone fragment, a finger bone that belonged to a girl with brown eyes, brown hair and brown skin who died in Siberia between 74,000 and 82,000 years ago.
By comparing the genetic sequences of these ancient hominins to modern humans and our primate relatives, researchers learn more about how these ancient species lived, acted, and evolved. The DNA even informed us that humans possibly interbred with both of these species, since we can find some of their DNA in the genome of some modern humans.

Physicists detect particles, known as Majorana fermions, that act as their own antiparticle.
An antiparticle is a subatomic particle that has the same mass as a given particle, but opposite electric or magnetic charge.
A group of physicists from the Netherlands provided the first evidence that the Majorana Fermion, a particle that has the unique property of being its own antiparticle, exists.
Scientists think "quantum bits" made of these mysterious particles could be more efficient at storing and processing data than the bits currently used in digital computers.

The ENCODE project revealed a ton of data to help us understand our genomes better.
The results of a gigantic biology project — called ENCODE — were released in early September. The project covered ten years of effort by over 400 scientists and has culminated in 30 scientific papers published today.
The data from the project is still being analyzed, but it will help us understand our own genomes, not just based on the sequence of letters in the DNA code, but how this DNA interacts with proteins and other strands of DNA and RNA. These interactions happen in the non-coding regions of the genome, which are kind of like the "dark matter" of our genome — they don't get turned into proteins (only about 1.5 percent of your DNA does), so researchers were unsure what roles they played.
They think they've found the functions of about 80 percent of these non-coding regions with the ENCODE survey.

A new tool helps researchers manipulate our genes.
In 2012 researchers created a remarkable protein that they can use to change a cell's genes on the fly. Known as TALENs, which stands for "transcription activator-like effector nucleases," gave researchers the ability to alter or inactivate specific genes in zebrafish, toads, livestock and other animals — even cells from patients with disease.
These TALENs can be customized to seek out and edit any DNA sequence, so it's very specific. It can be used to chop out a bad gene and replace it for a treatment, or can be used in research to understand what specific DNA stretches do in healthy and diseased individuals.

Paralyzed patients use their mind to move a robotic arm.
A sensor implanted in the brain's cortex and used to monitor brain signals was able to control a robotic arm. The prosthetic limb shown below responded when the user simply thought about moving his arm or hand.

Relive one of the greatest science stories of the year.
Red Bull Content Pool via National Geographic

Felix Baumgartner Breaks The Sound Barrier In A 24-Mile Plunge To Earth >


[Picture link HERE]



_______________________Reference
http://www.businessinsider.com/sciences-2012-breakthroughs-of-the-year-2012-12#the-discovery-of-the-higgs-boson-confirms-mainstream-physics-theories-10
http://www.businessinsider.com/astronauts-could-survive-radiation-on-mars-2012-12
http://www.businessinsider.com/the-latest-pictures-of-mars-look-exactly-like-something-from-earth-2012-8
http://www.businessinsider.com/encode-genome-data-and-human-genes-2012-9

http://www.businessinsider.com/felix-baumgartner-broke-records-with-his-skydive-2012-12
http://www.businessinsider.com/felix-baumgartner-broke-records-with-his-skydive-2012-12#preparations-for-the-big-launch-begin-before-sunrise-on-sunday-oct-14-the-weather-looks-good-for-an-early-launch-though-lift-off-is-eventually-delayed-two-hours-1

Friday, July 09, 2010

MooPig Feed for Thought "Genomics Department" :: Numbing NUMBERS

Report by Pat Darnell
UPDATE by PD

3 BILLION
About the number of base pairs in the human genome. The Human Genome Project was launched in 1990 and completed in 2003. The Project cost then about $2,700,000,000 [$2.7 billion] which is about a $-Dollar per Base Pair.

$48,000
San Diego company, Illumina, will sequence your entire genome for you, for this amount.

A new machine on the horizon will be able to do two full sequencings for only $10,000.

The Prize winner is going to be the invention of the machine that will " ... sequence 100 human genomes in 10 days for less that $10,000 each. ... " It's developer will be rewarded a prize of $10 million by the Archon X Prize Foundation.

About that paternity suit, Slick. You might want to just go ahead and pay the child care.

423
Sanger Institute's "Cancer Gene Census" figures there to be this many human genes implicated in cancers.

The WHO, World Health Organization, claims that over 10,000 human diseases may result from a single human gene. YIKES!

3 MILLION
Your FBI has about 8 million individual DNA profiles on record. Individuality is being re-defined ... only one-tenth of one-percent of the entire genome of individuals carries our traits for differences.

This number, 3 million, is the number of base pairs that differ from one person to another, according to our Genome Project.

5,831
As of late in 2009, this is how many genome sequencing projects are registered with GENOMES ONLINE:
  • 4,172 for Bacteria
  • 443 for Fungi
  • 233 for Plants
  • 37 for Primates
  • 84 for other mammals
  • 41 to Fish
  • 8 to Birds
160,000
Smallest known number of base pairs in the bacterium CARSONELLA RUDDI, living symbiotic with insects called PSYLLIDS -- which does not have the genes needed to survive on its own.

133 BILLION
The largest known number of base pairs in the largest genome, belonging to the Marbled Lungfish; Contrasting with only 3 billion base pairs in human sequencing. (discovermagazine. may, 2010)

UPDATE: [source]
Number of species/subspecies available: 4972 (3231 Vertebrates, 1741 Non-Vertebrates)
Smallest animal genome size: 0.02pg, Pratylenchus coffeae, Plant-parasitic nematode
Largest animal genome size: 132.83pg, Protopterus aethiopicus, Marbled lungfish
[NOTEs: Vinogradov (2005) recently argued that the largest genome size among animals is found in the South American lungfish Lepidosiren paradoxa at 80pg, and that Pedersen's (1971) measurement of the marbled lungfish Protopterus was greatly overestimated. However, Vinogradov did not measure P. aethiopicus, he measured P. dolloi. As a result, the largest animal genome reported remains 133pg for P. aethiopicus, followed by the amphibians Necturus lewisi and N. punctatus at 120pg*, followed by the amphibians Necturus maculosus and Amphiuma means and the lungfish Lepidosiren paradoxa (if one accepts Vinogradov's new estimate; three older studies placed it at 113-124pg), all at roughly 80pg.} Got That??
Next WEEK: WHO Knows ??

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